Through games of Feb. 6, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Randolph-Macon (25) | 20-1 | 625 | 1 |
| 2 | Marietta | 18-2 | 584 | 3 |
| 3 | UW-Oshkosh | 17-3 | 560 | 5 |
| 4 | Christopher Newport | 19-2 | 535 | 4 |
| 5 | UW-Platteville | 19-2 | 519 | 2 |
| 6 | St. Joseph (Conn.) | 18-0 | 496 | 7 |
| 7 | UW-La Crosse | 18-3 | 453 | 8 |
| 8 | Washington U. | 15-3 | 440 | 9 |
| 9 | Illinois Wesleyan | 16-4 | 411 | 10 |
| 10 | Mount Union | 18-2 | 384 | 11 |
| 11 | Maryville (Tenn.) | 17-1 | 376 | 12 |
| 12 | Williams | 14-1 | 317 | 13 |
| 13 | Wheaton (Ill.) | 17-4 | 284 | 15 |
| 14 | Oswego State | 20-1 | 233 | 17 |
| 15 | Yeshiva | 18-2 | 223 | 6 |
| 16 | Mary Hardin-Baylor | 16-2 | 218 | 18 |
| 17 | Swarthmore | 18-3 | 209 | 16 |
| 18 | Emory | 15-4 | 202 | 20 |
| 19 | Johns Hopkins | 16-3 | 162 | 19 |
| 20 | Elmhurst | 16-5 | 157 | 21 |
| 21 | Whitworth | 17-3 | 130 | 14 |
| 22 | WPI | 18-2 | 116 | 24 |
| 23 | Nazareth | 19-1 | 101 | 25 |
| 24 | Case Western Reserve | 16-3 | 93 | 23 |
| 25 | Mass-Dartmouth | 18-2 | 86 | -- |
Dropped out: No. 22 Augsburg.
Others receiving votes: Wesleyan 84; Heidelberg 40; Wabash 33; Berry 20; Augsburg 11; DeSales 7; Amherst 4; Chapman 4; LeTourneau 3; Middlebury 2; Trinity (Texas) 2; Nichols 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.