For the 2021-22 season, Division III realigned basketball into 10 regions. Region 9 is primarily teams from the Upper Midwest. To find other former West Region teams such as the NWC and SCIAC, check out Region 10 and to find other former Central Region teams such as the CCIW, NACC and SLIAC, check out Region 8.
| School | Location | Conference | Enrollment |
| Augsburg | Minneapolis, MN | MIAC | 2029 |
| Beloit | Beloit, WI | MWC | 1320 |
| Bethany Lutheran | Mankato, MN | UMAC | 628 |
| Bethel | Arden Hills, MN | MIAC | 2324 |
| Buena Vista | Storm Lake, IA | ARC | 1999 |
| Carleton | Northfield, MN | MIAC | 1975 |
| Central | Pella, IA | ARC | 1465 |
| Coe | Cedar Rapids, IA | ARC | 1249 |
| Concordia-Moorhead | Moorhead, MN | MIAC | 2815 |
| Cornell | Mount Vernon, IA | MWC | 998 |
| Crown | St. Bonifacius, MN | UMAC | 586 |
| Dubuque | Dubuque, IA | ARC | 1544 |
| Grinnell | Grinnell, IA | MWC | 1636 |
| Gustavus Adolphus | St. Peter, MN | MIAC | 2451 |
| Hamline | St. Paul, MN | MIAC | 1927 |
| Illinois College | Jacksonville, IL | MWC | 953 |
| Knox | Galesburg, IL | MWC | 1355 |
| Lake Forest | Lake Forest, IL | MWC | 1683 |
| Lawrence | Appleton, WI | MWC | 1415 |
| Loras | Dubuque, IA | ARC | 1440 |
| Luther | Decorah, IA | ARC | 1990 |
| Macalester | St. Paul, MN | MIAC | 1858 |
| Martin Luther | New Ulm, MN | UMAC | 611 |
| Minnesota-Morris | Morris, MN | UMAC | 1439 |
| Monmouth | Monmouth, IL | MWC | 1314 |
| Nebraska Wesleyan | Lincoln, NE | ARC | 1586 |
| North Central (Minn.) | Minneapolis, MN | UMAC | 751 |
| Northland | Ashland, WI | UMAC | 649 |
| Northwestern (Minn.) | Roseville, MN | UMAC | 1372 |
| Ripon | Ripon, WI | MWC | 816 |
| Simpson | Indianola, IA | ARC | 1474 |
| St. John's | Collegeville, MN | MIAC | 1462 |
| St. Mary's (Minn.) | Winona, MN | MIAC | 1207 |
| St. Olaf | Northfield, MN | MIAC | 3071 |
| St. Scholastica | Duluth, MN | MIAC | 2492 |
| UW-Eau Claire | Eau Claire, WI | WIAC | 8497 |
| UW-La Crosse | La Crosse, WI | WIAC | 8090 |
| UW-Oshkosh | Oshkosh, WI | WIAC | 8734 |
| UW-Platteville | Platteville, WI | WIAC | 5900 |
| UW-River Falls | River Falls, WI | WIAC | 3957 |
| UW-Stevens Point | Stevens Point, WI | WIAC | 6287 |
| UW-Stout | Menomonie, WI | WIAC | 6815 |
| UW-Superior | Superior, WI | UMAC | 1594 |
| UW-Whitewater | Whitewater, WI | WIAC | 8029 |
| Wartburg | Waverly, IA | ARC | 1729 |