Through games of Feb. 20, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Randolph-Macon (25) | 24-1 | 625 | 1 |
| 2 | Marietta | 22-2 | 595 | 2 |
| 3 | UW-Oshkosh | 20-3 | 574 | 3 |
| 4 | Christopher Newport | 22-2 | 550 | 4 |
| 5 | Illinois Wesleyan | 21-4 | 521 | 6 |
| 6 | UW-Platteville | 20-4 | 442 | 8 |
| 7 | Mary Hardin-Baylor | 22-2 | 406 | 9 |
| 8 | Mount Union | 21-3 | 405 | 10 |
| 9 | UW-La Crosse | 19-5 | 376 | 7 |
| 10 | Wheaton (Ill.) | 20-5 | 373 | 11 |
| 11 | Wesleyan | 22-3 | 363 | 13 |
| 12 | St. Joseph (Conn.) | 23-1 | 356 | 5 |
| 13 | Johns Hopkins | 20-3 | 336 | 12 |
| 14 | WPI | 22-2 | 307 | 16 |
| 15 | Emory | 18-5 | 291 | 18 |
| 16 | Wabash | 21-3 | 254 | 20 |
| 17 | Oswego State | 23-2 | 227 | 19 |
| 18 | Swarthmore | 21-4 | 193 | 21 |
| 19 | Elmhurst | 19-6 | 152 | 15 |
| 20 | Yeshiva | 22-3 | 146 | 24 |
| 21 | Williams | 16-3 | 131 | 22 |
| 22 | Maryville (Tenn.) | 20-3 | 127 | 14 |
| 23 | Berry | 21-2 | 102 | 23 |
| 24 | Mass-Dartmouth | 22-3 | 98 | -- |
| 25 | Stockton | 21-4 | 28 | -- |
Dropped out: No. 17 Washington U., No. 25 Case Western Reserve
Others receiving votes: St. John's 26; Whitworth 23; Guilford 18; Linfield 14; Washington U. 13; Rochester 10; Hope 8; LeTourneau 8; Pomona-Pitzer 7; Chapman 7; RPI 5; Middlebury 4; Hanover 2; Susquehanna 1; Trinity (Texas) 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.