Through games of Nov. 28, 2021:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Yeshiva (13) | 8-0 | 603 | 2 |
| 2 | Illinois Wesleyan (3) | 5-0 | 586 | 4 |
| 3 | Randolph-Macon (8) | 6-1 | 583 | 1 |
| 4 | UW-Platteville (1) | 7-0 | 562 | 5 |
| 5 | Wheaton (Ill.) | 6-0 | 471 | 6 |
| 6 | St. Joseph (Conn.) | 5-0 | 435 | 9 |
| 7 | Elmhurst | 6-0 | 420 | 10 |
| 8 | UW-La Crosse | 7-0 | 402 | 15 |
| 9 | Roanoke | 5-0 | 385 | 20 |
| 10 | UW-Oshkosh | 6-1 | 376 | 17 |
| 11 | Mary Hardin-Baylor | 3-0 | 354 | 12 |
| 12 | Mount Union | 5-0 | 351 | 21 |
| 13 | Marietta | 3-2 | 320 | 3 |
| 14 | Trine | 5-1 | 281 | 7 |
| 15 | Johns Hopkins | 5-1 | 271 | 14 |
| 16 | Whitworth | 5-1 | 253 | 19 |
| 17 | Christopher Newport | 5-2 | 221 | -- |
| 18 | Swarthmore | 4-1 | 220 | 8 |
| 19 | Wesleyan | 6-0 | 159 | -- |
| 20 | Washington U. | 5-1 | 146 | 18 |
| 21 | Amherst | 5-0 | 128 | -- |
| 22 | Emory | 3-2 | 105 | 13 |
| 23 | RPI | 4-0 | 78 | -- |
| 24 | Maryville (Tenn.) | 4-1 | 71 | 23 |
| 25 | DeSales | 6-0 | 59 | -- |
Others receiving votes: Berry 50; WPI 36; Lynchburg 29; Williams 23; Mass-Dartmouth 21; Cal Lutheran 21; Trinity (Texas) 19; Brandeis 18; Case Western Reserve 13; Wooster 12; Colby 9; Rochester 7; Dubuque 5; Linfield 5; UW-Eau Claire 4; Hanover 4; Calvin 3; LeTourneau 3; Baldwin Wallace 1; Catholic 1; Nichols 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.