Through games of Jan. 30, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Christopher Newport (16) | 17-0 | 600 | 2 |
| 2 | Trine (5) | 15-2 | 579 | 5 |
| 3 | Hope (3) | 17-1 | 576 | 1 |
| 4 | Transylvania (1) | 16-0 | 567 | 3 |
| 5 | Simpson | 17-1 | 531 | 5 |
| 6 | Whitman | 18-1 | 502 | 6 |
| 7 | Tufts | 15-2 | 455 | 8 |
| 8 | UW-Whitewater | 18-2 | 440 | 9 |
| 9 | John Carroll | 15-2 | 404 | 10 |
| 10 | New York University | 15-1 | 394 | 7 |
| 11 | Amherst | 13-2 | 348 | 11 |
| 12 | Baldwin Wallace | 13-3 | 338 | 14 |
| 13 | DePauw | 16-2 | 322 | 13 |
| 14 | Wisconsin Lutheran | 15-0 | 261 | 17 |
| 15 | Mary Hardin-Baylor | 16-2 | 241 | 20 |
| 16 | East Texas Baptist | 14-3 | 238 | 18 |
| 17 | Messiah | 15-2 | 203 | 24 |
| 18 | Catholic | 15-1 | 139 | 25 |
| 19 | Wartburg | 14-4 | 114 | 12 |
| 20 | UW-Eau Claire | 15-5 | 113 | 16 |
| 21 | Scranton | 17-2 | 95 | -- |
| 22 | St. John Fisher | 16-2 | 86 | 23 |
| 23 | Springfield | 16-2 | 79 | 15 |
| 24 | Trinity (Texas) | 16-2 | 76 | -- |
| 25 | Smith | 15-1 | 72 | -- |
Dropped out: No. 19 Marietta; No. 21 Bowdoin; No. 22 Hardin-Simmons
Others receiving votes: Marietta 68; Hardin-Simmons 63; Bowdoin 51; Gettysburg 44; UW-Oshkosh 28; Bates 15; UC Santa Cruz 14; Albion 13; DeSales 11; Texas-Dallas 11; Roger Williams 8; Gustavus Adolphus 7; WPI 7; Ohio Northern 5; Ithaca 4; Redlands 2; Augsburg 1
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.