Through games of Feb. 20, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Christopher Newport (19) | 22-0 | 613 | 1 |
| 2 | Hope (2) | 23-1 | 592 | 2 |
| 3 | Trine (2) | 22-2 | 574 | 3 |
| 4 | Transylvania (2) | 22-0 | 560 | 4 |
| 5 | Simpson | 23-1 | 530 | 5 |
| 6 | Whitman | 24-1 | 499 | 6 |
| 7 | New York University | 21-1 | 464 | 8 |
| 8 | Amherst | 20-2 | 429 | 9 |
| 9 | Tufts | 20-3 | 391 | 11 |
| 10 | DePauw | 22-2 | 388 | 12 |
| 11 | UW-Whitewater | 22-3 | 387 | 7 |
| 12 | John Carroll | 20-3 | 367 | 13 |
| 13 | Scranton | 23-2 | 271 | 17 |
| 14 | Baldwin Wallace | 18-4 | 267 | 10 |
| 15 | Trinity (Texas) | 23-2 | 207 | 18 |
| 16 | Mary Hardin-Baylor | 21-3 | 197 | 14 |
| 17 | Smith | 21-2 | 194 | 20 |
| 18 | Wartburg | 20-4 | 184 | 19 |
| 19 | Messiah | 20-3 | 146 | 16 |
| 20 | Wisconsin Lutheran | 20-1 | 140 | 15 |
| 21 | East Texas Baptist | 19-4 | 137 | 22 |
| 22 | St. John Fisher | 23-2 | 130 | 21 |
| 23 | Springfield | 21-3 | 92 | 24 |
| 24 | Ithaca | 22-3 | 57 | -- |
| 25 | Hardin-Simmons | 18-4 | 52 | 25 |
Dropped out: No. 23 Catholic
Others receiving votes: Gettysburg 39; Marietta 36; Trinity (Conn.) 31; UC Santa Cruz 28; UW-Oshkosh 28; DeSales 19; Webster 15; UW-Eau Claire 12; Millikin 11; Gustavus Adolphus 10; Rhodes 7; Catholic 6; Roger Williams 4; Washington & Jefferson 4; Elizabethtown 3; Augsburg 2; Puget Sound 2
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.