Through games of Jan. 9, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Hope (25) | 11-0 | 625 | 1 |
| 2 | Christopher Newport | 13-0 | 585 | 2 |
| 3 | Amherst | 8-0 | 554 | 3 |
| 4 | Transylvania | 10-0 | 528 | 4 |
| 5 | Simpson | 12-1 | 503 | 6 |
| 6 | Trine | 10-2 | 490 | 7 |
| 7 | Whitman | 10-1 | 488 | 5 |
| 8 | UW-Whitewater | 13-1 | 470 | 8 |
| 9 | Tufts | 10-1 | 440 | 9 |
| 10 | New York University | 10-0 | 371 | 11 |
| 11 | UW-Eau Claire | 11-3 | 334 | 10 |
| 12 | John Carroll | 9-2 | 303 | 12 |
| 13 | Wartburg | 10-2 | 280 | 14 |
| 14 | East Texas Baptist | 9-2 | 275 | 15 |
| 15 | Baldwin Wallace | 9-2 | 254 | 17 |
| 16 | DePauw | 11-2 | 238 | 16 |
| 17 | Bowdoin | 11-3 | 198 | 13 |
| 18 | Springfield | 12-0 | 193 | 20 |
| 19 | Hardin-Simmons | 10-2 | 141 | 21 |
| 20 | Mary Washington | 13-1 | 129 | 22 |
| 21 | UW-Oshkosh | 11-3 | 123 | 18 |
| 22 | Marietta | 12-1 | 120 | 24 |
| 23 | Wisconsin Lutheran | 9-0 | 88 | 25 |
| 24 | Texas-Dallas | 6-3 | 63 | 23 |
| 25 | St. John Fisher | 10-1 | 61 | 19 |
Dropped out: None
Others receiving votes: Messiah 46; Mary Hardin-Baylor 39; Catholic 31; Smith 28; Trinity (Texas) 22; Bates 17; Gettysburg 17; Roger Williams 17; Scranton 13; Augsburg 8; St. Lawrence 8; Puget Sound 7; UC Santa Cruz 5; Gustavus Adolphus 4; Millikin 3; Wheaton (Ill.) 3; Drew 1; Salisbury 1; Utica 1
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.