Through games of Jan. 29, 2006:
| # | Team | W-L | Pts. | Last Week |
| 1 | Wittenberg (15) | 18-1 | 611 | 1 |
| 2 | Wooster (7) | 18-1 | 605 | 2 |
| 3 | Lawrence (2) | 16-0 | 568 | 3 |
| 4 | Hope | 18-1 | 532 | 4 |
| 5 | Augustana (1) | 18-1 | 530 | 7 |
| 6 | Albion | 16-2 | 518 | 6 |
| 7 | Baldwin-Wallace | 17-2 | 449 | 8 |
| 8 | Illinois Wesleyan | 15-3 | 424 | 5 |
| 9 | York (Pa.) | 16-2 | 408 | 9 |
| 10 | Amherst | 16-2 | 365 | 10 |
| 11 | Wartburg | 17-2 | 340 | 13 |
| 12 | Occidental | 15-1 | 315 | 16 |
| 13 | Puget Sound | 15-3 | 302 | 12 |
| 14 | North Central | 15-3 | 280 | 11 |
| 15 | Worcester Polytech | 17-1 | 278 | 15 |
| 16 | Mississippi College | 17-1 | 238 | 17 |
| 17 | UW-Stout | 15-4 | 225 | 19 |
| 18 | Carnegie Mellon | 15-3 | 170 | 14 |
| 19 | Transylvania | 16-3 | 158 | 20 |
| 20 | Virginia Wesleyan | 18-3 | 142 | 23 |
| 21 | St. John Fisher | 15-3 | 135 | 22 |
| 22 | Lincoln | 18-4 | 98 | 24 |
| 23 | Carroll | 15-2 | 86 | 25 |
| 24 | UW-Oshkosh | 15-5 | 68 | 21 |
| 25 | Trinity (Conn.) | 15-3 | 58 | — |
Dropped out: No. 18 Randolph-Macon
Others receiving votes: Randolph-Macon 50, Elmhurst 48, Ohio Northern 33, Calvin 27, New York University 19, Rochester 10, Bates 8, UW-Whitewater 7, Southwestern 6, Maryville (Tenn.) 6, Willamette 4, Baruch 2, UW-La Crosse 1, Cortland State 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.