Through games of Jan. 15, 2006:
| # | Team | W-L | Pts. | Last Week |
| 1 | Wittenberg (15) | 14-1 | 610 | 1 |
| 2 | Wooster (3) | 14-1 | 592 | 3 |
| 3 | Albion (7) | 13-1 | 590 | 4 |
| 4 | Hope | 14-1 | 531 | 2 |
| 5 | Lawrence | 12-0 | 506 | 6 |
| 6 | Illinois Wesleyan | 12-2 | 478 | 5 |
| 7 | Puget Sound | 12-2 | 467 | 7 |
| 8 | York (Pa.) | 13-1 | 465 | 9 |
| 9 | Augustana | 14-1 | 453 | 10 |
| 10 | Baldwin-Wallace | 13-2 | 359 | 13 |
| 11 | Carnegie Mellon | 13-1 | 327 | 16 |
| 12 | Amherst | 10-2 | 318 | 8 |
| 13 | North Central | 12-1 | 289 | 12 |
| 14 | Worcester Polytech | 13-1 | 272 | 15 |
| 15 | Wartburg | 12-2 | 223 | 19 |
| 16 | St. John Fisher | 11-2 | 218 | 20 |
| 17 | Randolph-Macon | 13-3 | 207 | 14 |
| 18 | Mississippi College | 12-1 | 181 | 22 |
| 19 | Occidental | 11-1 | 155 | 24 |
| 20 | Hampden-Sydney | 12-2 | 105 | 11 |
| 21 | UW-Stout | 12-4 | 96 | 18 |
| 22 | Transylvania | 12-3 | 72 | 25 |
| 23 | UW-Whitewater | 11-3 | 68 | 23 |
| 24 | New York University | 12-1 | 66 | — |
| 25 | Ohio Northern | 11-3 | 64 | — |
Dropped out: No. 17 Wilmington, No. 21 Bluffton.
Others receiving votes: Bluffton 61, Maryville (Tenn.) 46, Carroll 40, Lincoln 38, Cortland State 30, Virginia Wesleyan 30, Elmhurst 29, UW-Stevens Point 28, UW-Oshkosh 25, Rochester 23, Trinity (Conn.) 22, Wilmington 17, St. Thomas 8, Hanover 7, Widener 6, William Paterson 2, Calvin 1, Loras 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.