Through games of Feb. 27, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Christopher Newport (19) | 24-0 | 608 | 1 |
| 2 | Hope (5) | 26-1 | 601 | 2 |
| 3 | Transylvania (1) | 24-0 | 563 | 4 |
| 4 | Simpson | 25-1 | 543 | 5 |
| 5 | Trine | 24-3 | 534 | 3 |
| 6 | Whitman | 26-1 | 513 | 6 |
| 7 | New York University | 22-1 | 478 | 7 |
| 8 | Amherst | 21-3 | 387 | 8 |
| 9 | Scranton | 25-2 | 370 | 13 |
| 10 | Baldwin Wallace | 21-4 | 350 | 14 |
| 11 | Tufts | 20-4 | 336 | 9 |
| 12 | UW-Whitewater | 23-4 | 329 | 11 |
| 13 | Trinity (Texas) | 25-2 | 290 | 15 |
| 14 | John Carroll | 22-4 | 284 | 12 |
| 15 | DePauw (`) | 23-3 | 282 | 10 |
| 16 | Smith | 23-2 | 278 | 17 |
| 17 | Messiah | 23-3 | 225 | 19 |
| 18 | Wisconsin Lutheran | 23-1 | 149 | 20 |
| 19 | Ithaca | 24-3 | 128 | 24 |
| 20 | St. John Fisher | 25-2 | 122 | 22 |
| 21 | Mary Hardin-Baylor | 22-4 | 115 | 16 |
| 22 | Hardin-Simmons | 21-4 | 107 | 25 |
| 23 | Wartburg | 21-5 | 104 | 18 |
| 24 | UW-Eau Claire | 21-7 | 86 | -- |
| 25 | Gettysburg | 24-3 | 69 | -- |
Dropped out: No. 21 East Texas Baptist; No. 23 Springfield
Others receiving votes: East Texas Baptist 64; UC Santa Cruz 46; DeSales 37; Springfield 21; Rhodes 18; Gustavus Adolphus 15; Cortland 13; Millikin 10; Bates 8; Trinity (Conn.) 8; Roger Williams 7; UW-Oshkosh 7; Webster 7; Marietta 6; Washington & Jefferson 6; Illinois Wesleyan 1
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.