Through games of Jan. 23, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Hope (25) | 16-0 | 625 | 1 |
| 2 | Christopher Newport | 16-0 | 592 | 2 |
| 3 | Transylvania | 14-0 | 558 | 3 |
| 4 | Trine | 13-2 | 535 | 5 |
| 5 | Simpson | 15-1 | 530 | 4 |
| 6 | Whitman | 16-1 | 493 | 8 |
| 7 | New York University | 14-0 | 477 | 9 |
| 8 | Tufts | 13-2 | 420 | 10 |
| 9 | UW-Whitewater | 16-2 | 414 | 6 |
| 10 | John Carroll | 13-2 | 367 | 12 |
| 11 | Amherst | 10-2 | 346 | 7 |
| 12 | Wartburg | 14-2 | 317 | 13 |
| 13 | DePauw | 14-2 | 296 | 14 |
| 14 | Baldwin Wallace | 11-3 | 279 | 11 |
| 15 | Springfield | 16-0 | 278 | 15 |
| 16 | UW-Eau Claire | 14-4 | 194 | 18 |
| 17 | Wisconsin Lutheran | 13-0 | 193 | 21 |
| 18 | East Texas Baptist | 12-3 | 190 | 20 |
| 19 | Marietta | 15-2 | 148 | 16 |
| 20 | Mary Hardin-Baylor | 14-2 | 139 | 24 |
| 21 | Bowdoin | 14-3 | 128 | 19 |
| 22 | Hardin-Simmons | 12-3 | 95 | 17 |
| 23 | St. John Fisher | 14-1 | 94 | 25 |
| 24 | Messiah | 13-2 | 58 | -- |
| 25 | Catholic | 13-1 | 52 | -- |
Dropped out: No. 22 Mary Washington; No. 23 UW-Oshkosh
Others receiving votes: Trinity (Texas) 48; Smith 42; Scranton 35; Texas-Dallas 31; Gettysburg 22; Bates 21; Roger Williams 20; Albion 17; Mary Washington 16; Carroll 15; Augsburg 14; Gustavus Adolphus 5; WPI 5; Puget Sound 4; UC Santa Cruz 4; Ohio Northern 3; UW-Oshkosh 3; Calvin 1; Redlands 1
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.