Through games of Jan. 17, 2010:
| # | Team | W-L | Pts. | Last Week |
| 1 | Illinois Wesleyan (20) | 15-0 | 620 | 1 |
| 2 | Amherst (4) | 15-0 | 597 | 2 |
| 3 | Washington U. | 13-1 | 569 | 3 |
| 4 | Kean (1) | 17-1 | 560 | 4 |
| 5 | Hope | 14-1 | 512 | 6 |
| 6 | Scranton | 12-2 | 479 | 7 |
| 7 | George Fox | 13-2 | 440 | 10 |
| 8 | Messiah | 14-1 | 389 | 14 |
| 9 | Calvin | 14-1 | 379 | 17 |
| 10 | Marymount | 15-1 | 372 | 5 |
| 11 | William Paterson | 16-1 | 369 | 13 |
| 12 | Muhlenberg | 10-2 | 339 | 9 |
| 13 | Bowdoin | 12-2 | 325 | 8 |
| 14 | Moravian | 13-2 | 292 | 16 |
| 15 | Christopher Newport | 15-0 | 239 | 20 |
| 16 | Tufts | 13-2 | 221 | 11 |
| 17 | Thomas More | 13-2 | 214 | 19 |
| 18 | Puget Sound | 13-2 | 202 | 22 |
| 19 | Carthage | 12-3 | 175 | 12 |
| 20 | UW-Stevens Point | 13-3 | 157 | 24 |
| 21 | UW-River Falls | 14-2 | 144 | 18 |
| 22 | UW-Whitewater | 12-4 | 115 | 15 |
| 23 | Washington and Jefferson | 13-2 | 95 | — |
| 24 | Gettysburg | 13-1 | 76 | 21 |
| 25 | Colby | 11-1 | 34 | — |
Dropped out: No. 23 Howard Payne, No. 25 Emmanuel.
Others receiving votes: Lewis and Clark 32, Chicago 28, DePauw 27, Howard Payne 27, Mount Union 27, Louisiana College 20, Mary Washington 16, Cal Lutheran 7, Simpson 7, Farmingdale State 6, Emmanuel 3, Rochester 3, Western Connecticut 2, Austin 1, Baldwin-Wallace 1, Elmhurst 1, Gustavus Adolphus 1, Lebanon Valley 1, St. Norbert 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.