Through games of Sunday, Feb. 21, 2021:
Because of the smaller number of teams playing during the COVID-19 pandemic, this poll is limited to 15 teams. Nobody beyond 15 is considered ranked. Only teams which have played a game are eligible to receive votes. With the changing nature of the pandemic, the number of voters and teams voted for may change from week to week.
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Hope (12) | 10-0 | 222 | 1 |
| 2 | East Texas Baptist (3) | 19-0 | 208 | 2 |
| 3 | Trine | 11-1 | 190 | 5 |
| 4 | Wartburg | 11-1 | 160 | 6 |
| 5 | Oglethorpe | 7-1 | 130 | 4 |
| 6 | Whitman | 5-1 | 123 | 3 |
| 7 | Millsaps | 9-1 | 115 | 8 |
| 8 | Hardin-Simmons | 12-3 | 97 | 9 |
| 9 | Texas-Dallas | 9-3 | 93 | 10 |
| 10 | Maryville (Tenn.) | 10-0 | 87 | 12 |
| 11 | DePauw | 5-1 | 79 | 7 |
| 12 | John Carroll | 9-1 | 76 | 11 |
| 13 | Wheaton (Ill.) | 9-1 | 52 | 14 |
| 14 | Simpson | 6-0 | 48 | 13 |
| 15 | UW-Eau Claire | 6-0 | 39 | 15 |
Dropped out: None
Others receiving votes: Messiah 24; Salisbury 12; Babson 9; St. Thomas (Minn.) 8; N.C. Wesleyan 7; Baldwin Wallace 6; Millikin 4; DeSales 3; Randolph Macon 3; Ohio Wesleyan 2; Scranton 2; LaGrange 1
The D3hoops.com Top 25 is voted on by a panel of 15 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 15-14-13-etc. basis.
Because of the changing nature of the pandemic, the number of voters and teams voted for may change from week to week.