Through games of Sunday, March 7, 2021:
Because of the smaller number of teams playing during the COVID-19 pandemic, this poll is limited to 15 teams. Nobody beyond 15 is considered ranked. Only teams which have played a game are eligible to receive votes. With the changing nature of the pandemic, the number of voters and teams voted for may change from week to week.
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Hope (14) | 16-0 | 224 | 1 |
| 2 | East Texas Baptist (1) | 23-0 | 206 | 2 |
| 3 | Trine | 14-3 | 186 | 3 |
| 4 | Wartburg | 13-2 | 145 | 4 |
| 5 | Oglethorpe | 7-1 | 141 | 5 |
| 6 | Millsaps | 11-1 | 140 | 6 |
| 7 | Simpson | 9-0 | 132 | 10 |
| 8 | Texas-Dallas | 13-3 | 114 | 9 |
| 9 | DePauw | 8-1 | 104 | 8 |
| 10 | Wheaton (Ill.) | 11-1 | 76 | 11 |
| 11 | Hardin-Simmons | 16-4 | 73 | 7 |
| 12 | Messiah | 8-0 | 62 | 13 |
| 13 | Whitman | 8-2 | 39 | 12 |
| 14 | John Carroll | 13-2 | 33 | 14 |
| 15 | Maryville (Tenn.) | 12-2 | 15 | -- |
Dropped out: No. 15 UW-Eau Claire
Others receiving votes: Babson 14; UW-Oshkosh 14; St. Thomas (Minn.) 13; UW-Eau Claire 13; DeSales 12; N.C. Wesleyan 10; Gustavus Adolphus 9; Piedmont 9; Salisbury 8; Millikin 5; Scranton 2; UW-Whitewater 1
The D3hoops.com Top 25 is voted on by a panel of 15 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 15-14-13-etc. basis.
Because of the changing nature of the pandemic, the number of voters and teams voted for may change from week to week.