Entering 2005-06 season:
| # | Team | W-L | Pts. | Last Week |
| 1 | Millikin (19) | 29-2 | 614 | 1 |
| 2 | Randolph-Macon (2) | 30-2 | 589 | 2 |
| 3 | Bowdoin | 26-3 | 548 | 5 |
| 4 | Southern Maine (4) | 31-3 | 539 | 3 |
| 5 | Scranton | 31-3 | 505 | 4 |
| 6 | UW-Stout | 24-7 | 381 | 9 |
| 7 | Capital | 20-6 | 355 | — |
| 8 | Brandeis | 23-4 | 325 | 21 |
| 9 | St. Benedict | 24-5 | 308 | 17 |
| 10 | George Fox | 22-6 | 293 | 12 |
| 11 | Wheaton (Ill.) | 22-4 | 287 | 20 |
| 12 | Springfield | 25-6 | 275 | 22 |
| 13 | Emmanuel | 27-3 | 272 | 16 |
| 14 | Washington U. | 22-5 | 266 | 8 |
| 15 | Hope | 23-4 | 248 | — |
| 16 | Buena Vista | 25-3 | 235 | 19 |
| 17 | Bates | 25-3 | 183 | 6 |
| 18 | Washington and Jefferson | 21-7 | 180 | — |
| 19 | Moravian | 24-6 | 161 | — |
| 20 | Baldwin-Wallace | 23-6 | 143 | — |
| 21 | UW-Stevens Point | 21-6 | 134 | — |
| 22 | DePauw | 23-6 | 129 | 18 |
| 23 | McDaniel | 25-4 | 124 | 14 |
| 24 | Hardin-Simmons | 22-4 | 118 | 23 |
| 25 | Messiah | 25-4 | 100 | 10 |
Others receiving votes: Wesleyan 83, New York University 79, King's 78, UW-Oshkosh 71, Mary Washington 61, Simpson 59, Albion 59, Wilmington 51, Oswego State 40, Dickinson 40, Trinity (Texas) 35, Calvin 32, McMurry 31, Illinois Wesleyan 31, William Smith 24, Chicago 11, Howard Payne 8, St. John Fisher 5, Concordia-Moorhead 5, Carleton 4, Ripon 3, Franklin 1, Rhodes 1, Williams 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.